摘要
Bcl-2编码的蛋白具有潜在的抑制凋亡作用,在一半以上的肿瘤中可见其异常表达。反义治疗可以抑制Bcl-2基因的表达,诱导凋亡或提高化疗敏感性。
The protein encoded by bcl - 2 is a potent suppressor of apoptosis and is found at inappropriately high levels in probably more than half of all cancers in humans. Antisense oligonucleotide therapy has been used to inhibit the expression of Bcl -2 gene, aimed to induce apoptosis or enhance chemosensitivity.
出处
《现代肿瘤医学》
CAS
2011年第2期382-385,共4页
Journal of Modern Oncology
