摘要
目的 :探讨我国青年女性冠心病患者的临床特点。方法 :将 4 0岁以下 (含 4 0岁 )经冠状动脉 (冠脉 )造影确诊的女性冠心病患者 (13例 )与同期确诊的青年男性患者 (4 9例 )及青年女性非冠心病者 (8例 )进行对照研究 ,分析其临床特点。结果 :女性冠心病组患者症状多不典型 (分别为53.85%、6 .12 % ,P <0 .0 1) ;多支病变者显著少于男性组 (0、53.0 6 % ,P =0 .0 17) ;冠脉病变积分亦显著低于男性组 ,分别为 (7.15± 3.16 )、(12 .84± 5.4 7)分 ,P <0 .0 5,前降支受累多见。冠心病组有冠心病家族史者显著多于非冠心病组 (4 6 .15%、0 ,P=0 .0 32 ) ,血总胆固醇水平亦显著高于后者 (5.4 9± 1.94、3.80± 0 .55,P <0 .0 5)。结论 :冠心病家族史和血胆固醇水平增高为青年女性冠心病不可忽视的危险因素。
Objective:To study the clinical characters of young women with coronary artery disease (CAD).Method:Seventy adults under 40 years old were divided into 3 groups according to gender and results of coronary angiography:women with angiographic CAD (group Ⅰ,n=13) and women with non CAD (group Ⅱ as controls,n=8).Group Ⅰ was also compared with men with angiographic CAD (group Ⅲ,n=49).The CAD risk factors were also studied.Result:Compared with group Ⅲ ,group Ⅰ had a lower incidence of multivessel disease (0、 53.06 %,P= 0.017 ) and a lower coronary severity score ( 7.15 ± 3.16 、 12.84 ± 5.47 ,P< 0.05 ),and atypical clinical signs in most of them ( 53.85 %、 6.12 %,P< 0.01 ).Compared with group Ⅱ,group Ⅰ had a higher incidence of positive family history of CAD ( 46.15 %、0,P= 0.032 ) and a higher level of total blood cholesterol ( 5.49 ± 1.94 、 3.80 ± 0.55 ,P< 0.05 ).Conclusion:Positive CAD family history and high level of total blood cholesterol are the main risk factors of young females with CAD,and clinical signs are atypical in most of them.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
1999年第5期206-208,共3页
Journal of Clinical Cardiology
关键词
冠心病
青年女性
危险因素
临床特点
Coronary artery disease Young women Coronary angiography Risk factors
