摘要
目的：探讨国人４０岁以下冠心病患者的冠状动脉（冠脉）病变特点及其危险因素。方法：根据冠脉造影结果将４０岁以下行冠脉造影的６８例分为冠心病组（４６例）和非冠心病组（２２例），分析其冠脉病变特点并将危险因素加以对照。结果：前降支受累率最高，为７６％；男性患者中，多支病变者多于女性（Ｐ＜０．０５），冠脉病变积分高于女性（１１．８２±５．４４ｖｓ．７．１０±３．１５，Ｐ＜０．０５）。冠心病家族史和血胆固醇水平为冠心病的主要危险因素，比值比分别为３．９８（９５％可信区间１．３８～１１．５１），２．０９（９５％可信区间１．２６～３．４６）。冠脉病变积分与男性、胆固醇水平呈正相关，相关系数分别为０．３６６和０．３５４，Ｐ均＜０．０５。结论：冠脉病变男性重于女性，青年冠心病患者的冠心病家族史是不可忽视的重要危险因素。
Objective:To study lesions of coronary artery in patients with coronary artery disease(CAD)under 40 years old and the risk factors. Methods:Sixty eight adults under 40 years old who had undergone coronary angiography (CAG) were divided into 2 groups:Group I( n =46) with evidence of angiographic CAD and group II ( n =22)with non CAD as control.The CAD risk factors were also studied. Results:In group I,left anterior descending artery was common(35/46,76%),male patients had a high incidence of multivessel disease(57% vs.30%, p <0 05).Family history of CAD and total blood cholesterol level were the main risk factors,the odd ratios(OR) were 3 98[95% confidence interval(CI)1 38—11 51]and 2 09(95% CI 1 26—3 46),respectively.A positive correlation was present in angiographic score and males as well as total cholestreol level. Conclusions:Lesions of coronary artery are more severe in males than in females.Family history of CAD is a very important risk factor in young patients.
出处
《中国循环杂志》
CSCD
北大核心
1997年第5期337-339,共3页
Chinese Circulation Journal
关键词
冠心病
冠状动脉造影
危险因素
Coronary artery disease
Young adult
Angiography
Risk factors
