摘要
目的观察醒脑阴阳透刺法对急性脑梗死(ACI)患者血清中Ca2+含量的影响。方法将2009年3月-2009年12月在贵州省人民医院神经内科住院的符合1995年中华医学会第4届脑血管学术会议修订的《各类脑血管病诊断要点的ACI患者60例随机分为醒脑阴阳透刺组(A组)、头针组(B组)与单纯药物组(C组),采用钙离子选择性电极,用电解质分析仪测定治疗前后的血清Ca2+浓度并进行神经功能缺损程度评分。结果与治疗前比较,3组治疗后神经功能缺损程度评分减少,Ca2+含量升高,A、B组治疗后与C组比较差异有统计学意义,其中A组与B组比较差异亦有统计学意义。结论醒脑阴阳透刺法能促进ACI患者神经功能缺损的恢复,改善患者的临床症状,提高生活质量,其作用机制可能是通过升高血清Ca2+含量,降低神经元毒性,抑制细胞内钙超载,阻断和减弱脑缺血级联反应,改善脑部血液循环,从而达到对ACI患者的脑保护作用。
Objective：To observe the Xingnaoyinyang Penetration Needling Method on the level of Ca2＋ in serum of patients with acute cerebral infarction.Methods： 60 cases of acute cerebral infarction were randomly divided into the A group with the Xingnaoyinyang Penetration Needling Method,the B group with scalp acupuncture and the C group with drug only.The calcium ion selective electrode and the electrolyte analyzer were used to detect the Ca2＋ in serum.Meanwhile,the score of neurological deficits were observed before and after treatment.Results： In 3 groups,these scores of neurological function were decreased and these Ca2＋ levels were increased after treatment.There were some significant differences in the A,B and C group.Also,there was a statistical difference between the A group and the B group.Conclusion： The neurological functions of the acute cerebral infarction patients were improved by the Xingnaoyinyang Penetration Needling Method.This therapy could ameliorate the clinical symptoms and increase the life quality.These protective effects could be through some pathways including increase the Ca2＋ content in serum,reduction of neuron toxicity,inhibition the intracellular calcium overload,blocking and decrease the cerebral ischemic cascade reaction and improvement of cerebral blood circulation.
出处
《中国中医急症》
2011年第1期9-11,共3页
Journal of Emergency in Traditional Chinese Medicine
关键词
脑梗死
CA2+
神经功能缺损程度评分
醒脑阴阳透刺法
Cerebral infarction
Ca2＋
Score of neurological deficits
Xingnaoyinyang Penetration Needling Method
