摘要
合成了一个新的希夫碱大环配体硝酸Ho(Ⅲ)配合物[Ho(H2L)(NO3)2](NO3)(H2L表示大环配体),并进行了系统的物理表征.晶体结构研究表明,配合物晶体结构属六方晶系,P3121空间群,晶胞参数a=1.47213(7)nm,c=2.8998(3)nm,α=90°,γ=120°,V=5.4424(7)nm3,Z=6,R=0.0331,wR=0.0928.中心离子Ho3+位于隔室大环配体的一侧,并与希夫碱大环上的2个酚基氧原子和3个氮原子配位,2个双齿配位硝酸根分别从希夫碱大环平面的两侧与中心离子配位,使中心离子形成扭曲的九配位三冠三棱柱构型.通过凝胶电泳实验初步研究了该配合物对pBR322质粒DNA的切割作用.
A macrocyclic complex [Ho（H2L）（NO3）2]（NO3）（H2L denotes the macrocyclic ligand） was synthesized and characterized by elemental analysis,infrared spectra and electrospray mass spectra.Its crystal and molecular structures were characterized by X-ray diffraction methods.The crystal crystallizes in the hexagonal system,space group P3121 with a=1.47213（7） nm,c=2.8998（3） nm,α=90°,γ=120°,V=5.4424（7） nm3,Z=6,R=0.0331,wR=0.0928.The central holmium ion is located in one of the compartments of the macrocyclic ligand and is coordinated with two oxygen and three nitrogen atoms of the macrocycle.Two nitrates are chelated in the opposite positions of the macrocycle,and the third one is ionic.So the central ion presents a distorted tricapped trigonal prismatic coordination geometry.The preliminary studies of cleavage of double stranded DNA were demonstrated by electrophoresis gel.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2010年第12期2344-2348,共5页
Chemical Journal of Chinese Universities
基金
国家自然科学基金(批准号:20671075)资助
关键词
希夫碱大环
钬
配合物
晶体结构
DNA
Schiff-based macrocycle
Holmium
Complex
Crystal structure
DNA
