摘要
目的:探讨女性生殖道支原体感染率及耐药趋势,为临床诊断和治疗提供依据,指导临床合理用药。方法:采用支原体分离、鉴定、药敏一体化检测试剂盒对云南省妇幼保健院5年来妇科门诊的标本进行支原体(Uu、Mh)培养及药敏试验。结果:支原体近5年的总感染率为62.68%,对红霉素(97.44%)、罗红霉素(87.18%)和环丙沙星(76.92%)耐药率高,对强力霉素、美满霉素敏感(>80%);Uu和Mh复合感染比单纯感染耐药率明显增高。结论:支原体对常用抗生素的耐药性呈上升趋势,Mh和Uu复合感染比单纯感染有较高耐药性,因此,临床诊治前应尽可能做支原体培养及药敏试验,合理、规范用药以延缓耐药株的快速增加。
Objective：To explore the rate of female genital mycoplasma infection and the trend of drug resistance, provide a basis for clinical diagnosis,treatment and direct rational drug use in clinic.Methods：Integrated kit with the function of isolation, incubation and identification was used for mycoplasma cultivation （Uu and Mh） and drug sensitivity test of samples from gynecologic outpatient department in recent 5 years.Results：The total infection rate of mycoplasma was 62.68%.The drug resistance rates of erythromycin, roxithromycin and ciprofloxacin were 97.44%, 87.18% and 76.92%,respectively, doxycycline and minocin were sensitive （〉80%）; the drug resistance rate of mixed infection of Uu plus Mh was higher than that of simple infection.Conclusion：The drug resistance of mycoplasma to common antibiotics has a rising trend, the drug resistance rate of mixed infection of Uu plus Mh is higher than that of simple infection. Therefore, mycoplasma cultivation and drug sensitivity test before clinical diagnosis and treatment are necessary, reasonable and standard medication may slow down the increase of strong resistant bacteria.
出处
《中国妇幼保健》
CAS
北大核心
2010年第35期5227-5229,共3页
Maternal and Child Health Care of China
关键词
女性生殖道
支原体
耐药
感染率
Female genital tract
Mycoplasma
Drug resistance
Infection rate
