摘要
目的探讨血清总前列腺特异抗原(TPSA)、游离前列腺特异抗原(FPSA)和FPSA/TPSA比值(F/T比值)在前列腺癌诊治中的应用价值。方法使用Liaisin全自动化学发光免疫分析仪检测经临床确诊的42例前列腺癌(PCa)和84例良性前列腺增生(BPH)患者和62例健康者血清TPSA、FPSA含量,并计算F/T。结果 PCa组患者TPSA、FPSA水平均明显升高。BPH与PCa两组患者间在诊断灰区内差异无统计学意义(P>0.05),而F/P比值差异有统计学意义(P<0.01)。结论在前列腺癌诊治中,T/P比值的诊断价值,明显优于单纯使用TPSA。
Ojective To research the clinical application of serum prostate specific antigen（PSA）,free-prostate specific antigen（f-PSA）and（f-PSA）/（PSA）ratio for the diferential diagnosis of prostatic carcinoma（PCa）.Methods Serum samples were obtained from 62 normal men,42 patients with prostatic carcinoma（PCa）and 84 patients with untreaded benign prostate hyperplasia（BPH）.The levels of PSA and f-PSA in serum were determined by auto-immunochemieal luminescence method,and the ratio of f-PSA/ PSA was calculated.Results The various indexes of the PCa group were signifieamly higher than those of the control group.The difference of PSA had no statistical significonce between the PCa and BPH groups（P〉0.05）.The FPSA/PSA ratio had statistical difference between PCa group and BPH group（P〈0.01）.Conclusion The ratio of PSA/PSA is superior to simple PSA in the diagnosis of prostatic carcinoma（PCa）.
出处
《重庆医学》
CAS
CSCD
北大核心
2010年第22期3061-3062,共2页
Chongqing medicine
关键词
前列腺特异抗原
前列腺癌
前列腺增生
prostate specific antigen
prostate carcinoma
benign prostate hyperplasia
