摘要
目的探讨医院感染鲍氏不动杆菌(ABA)的耐药性,为临床医师合理用药提供科学依据。方法 219株ABA培养与鉴定严格按照《全国临床检验操作规程》进行;药敏试验和结果判读采用CLSI推荐的K-B法和折点标准。结果 ABA在各类标本中检出率居前3位的分别是:痰液和下呼吸道分泌物(68.5%),脓液(11.4%)、脑脊液(10.0%);药敏结果显示,ABA对常用的14种抗菌药物耐药性已十分严重,对亚胺培南和美罗培南耐药率达到17.8%和18.3%,ABA泛耐药株检出率为3.2%。结论医院应加强细菌耐药性的监测与控制,预防耐药菌株医院感染暴发流行。
OBJECTIVE To approach the drug-resistance of Acinetobacter baumannii （ABA） in nosocomial infections to provide the scientific evidence for clinically reasonable application of antibiotics. METHODS Referring to Rules of Operation in Clinical Laboratory of Nationwide, 219 ABA were cultured and identified. And drugsensitivity testing was performed by K-B methods recommended by CLSI. RESULTS The top 3 detection rates in various kinds of specimens were as followed：sputum and secretion from lower respiratory tract （68.5%）, liquor puris（11.4%） and cerebrospinal fluid （10.0%）. The drug-resistance of ABA to 14 common antibiotics was very serious. The rate of drug-resistance to imipenem and meropenem had arrived at 17.8% and 18.3%, respectively. The detection rate of pan-drug resistant strains of ABA was 3. 2%. CONCLUSIONS The hospital should strengthen the monitoring and controlling of the bacterial drug-resistance and prevent the outbreak of nosocomial infections with resistant strains.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第22期3588-3589,共2页
Chinese Journal of Nosocomiology
关键词
鲍氏不动杆菌
医院感染
耐药性
监测
Acinetobacter baumannii
Nosocomial infections
Drug-resistance
Monitoring
