摘要
目的探讨应用双能X线吸收法(DXA)进行人体脂肪含量测量的可行性,并研究糖耐量低减的老年男性患者中脂肪含量与骨密度的相关性。方法选取171例糖耐量低减的老年男性行腰椎、股骨及全身的DXA检查,收集测量的骨密度、脂肪含量百分比、组织厚度及体重指数(BMI)等数据进行相关性统计分析。结果腰椎骨密度与腹部脂肪含量(fat%腹部)呈正相关,相关系数r=0.263(P<0.001);股骨颈骨密度与臀部脂肪含量(fat%臀部)呈负相关,r=-0.284(P<0.001)。fat%腹部、fat%臀部与BMI高度相关,r=0.561,0.377(P<0.001);腹部、臀部组织厚度与BMI高度相关,r分别为0.854,0.850(P<0.001)。结论 DXA测量所得的脂肪含量百分比及组织厚度可作为肥胖检测的定量指标,更多应用于临床;脂肪成分对骨密度具有双重影响,其机制尚待进一步研究。
Objective To explore the feasibility of using dual-energy X-ray absorptiometry （DXA） to measure the fat content of human body and to study the relationship between the fat content and the bone mineral density （BMD） in elderly males with impaired glucose tolerance （IGT）. Methods DXA examination was conducted to measure the lumbar vertebra, the femur, and all over the body of 171 elderly males with IGT. The data of BMD, fat content percentage, tissue thickness, and body mass index （BMI） were accumulated and analyzed statistically. Results The BMD of the lumbar vertebra was positively correlated with the fat content of the abdomen （r = 0. 263, P 〈 0. 001 ）. The BMD of the femur was negatively correlated with the fat content of the buttock （ r = 0. 284, P 〈 0. 001 ）. The percentage of fat content of both the abdomen and the buttock were highly correlated with BMI （r = 0. 561 and r = 0. 377, respectively, P 〈 0. 001 ）. The thickness of tissue of both the abdomen and the buttock were highly correlated with BMI （r = 0. 854 and r = 0. 850, respectively, P 〈 0. 001 ）. Conclusions The percentage of fat content and thickness of tissue measured using DXA can be considered as quantitative criteria of obesity and should be applied more in the clinic. The fat content has double-effect on BMD. The mechanism of this effect needs to be explored further.
出处
《中国骨质疏松杂志》
CAS
CSCD
2010年第10期727-729,共3页
Chinese Journal of Osteoporosis
