摘要
目的探讨中老年女性原发性良性阵发性位置性眩晕（BPPV）和骨质疏松之间的关系。方法选择48例年龄在50~80岁之间的原发性BPPV女性患者为BPPV组,同时选择同年龄段的83例正常女性作为对照组。通过双能X线吸收法对腰椎及股骨颈骨密度（BMD）的测定（采用T-值评分计算）来诊断骨质疏松或骨质减少。将两组按年龄段分为3个亚组,分别测定BMD后记录比较。结果在39例单侧BPPV患者中,骨质疏松有14例（35.89%）、骨质减少有15例（38.46%）;在9例双侧BPPV患者中,诊断骨质疏松有6例（66.67%）、诊断骨质减少有2例（22.22%）。对照组无BPPV的83例健康女性中,骨质疏松有15例（18.07%）、骨量减少有19例（22.89%）。年龄在50~59岁的BPPV组中骨质疏松或骨质减少占62.13%,年龄在60~69岁的BPPV组中骨质疏松或骨质减少占72.36%,年龄在70~80岁的BPPV组中骨质疏松或骨质减少占84.52%。BPPV组在50~59岁、60~69岁和70~80岁这三组年龄层次的T值均低于对照组,差异均有统计学意义（t分别=3.52、2.01、3.55,P均〈0.05）。结论中老年女性原发性BPPV和骨质疏松之间存在明显相关性,存在共同的病理生理机制。
Objective To research the relationships between benign paroxysmal positional vertigo（BPPV） and osteoporosis in middle-age and old women. Methods Forty-eight BPPV women whose age ranged from 50 to 80 years were selected as BPPV group, and 83 cases of normal women as control group. The diagnosis of osteoporosis or osteopenia was di-agnosed by a bone mineral density through dual X-ray absorptiometry of spine and hip（T-score）.The T-score were compared among three subgroups according to different age range. Results In 39 cases with unilateral BPPV, 14 patients of osteoporosis（35.89%） and 15 patients of osteopenia（38.46%）. In 9 cases with bilateral BPPV, 6 patients of osteoporosis（66.67%）and 2 patients of osteopenia（22.22%）.In 83 patients of control group, 15 patients of osteoporosis（18.07%） and19 patients of osteopenia（22.89%）. 62.13% patients of osteoporosis or osteopenia were found in BPPV group at the age range from 50 to 59 years, 72.36% of patients at the age range from 60 to 69 years, and 84.52% of patients at the age range from 70 to 80 years. The T-scores among subgroups of 50 to 59 years old, 60 to 69 years old and 70 to 80 years old in BPPV group were significantly lower than control group（t=3.52,2.01,3.55,P〈0.05）. Conclusion BPPV and osteoporosis in middle-age and old women has obvious relationship, which has common pathophysiological mechanisms.
出处
《全科医学临床与教育》
2016年第3期264-266,270,共4页
Clinical Education of General Practice
基金
浙江省医药卫生科技项目(2015ZHB014)
