摘要
目的评价总胆固醇/高密度脂蛋白胆固醇(TC/HDL-C)比值预测冠心病危险程度的价值。方法回顾性分析250例冠心病患者的临床资料分为:稳定型心绞痛组(SA组),不稳定型心绞痛组(UA组),并另选125例健康者为对照组,测定两组的TC/HDL-C、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)和HDL-C并比较其差异性和异常率。结果 SA组及UA组TC、TG、LDL-C及TC/HDL-C均高于对照组(P<0.01),HDL-C低于对照组(P<0.01),HDL-C分别为(1.08±0.36)mmol/L、(1.03±0.29)mmol/L vs(1.66±0.67)mmol/L,SA组、UA组HDL-C、LDL-C及TC/HDL-C异常率与对照组比较差异有统计学意义(P<0.05),分别为36.9%、39.1%vs 20.0%,32.0%、32.8%vs 16.0%,65.6%、72.7%vs 38.6%。结论 TC/HDL-C作为冠心病危险因素的预测价值和灵敏度高于单项血脂指标。
Objective To assess the value of measuring total cholesterol/high-density lipoprotein cholesterol（TC/HDL-C） ratio for predicting coronary heart disease（CHD）.Methods Two hundred and fifty patients with CHD were selected in the study.Patients were divided into stable angina pectoris group,unstable angina pectoris group.Health volunteers served as controls（n=125）.TC/HDL-C ratio and TC,TG,HDL-C and LDL-C levels were measured and compared.Results TC,TG,LDL-C and TC/HDL-C in stable angina pectoris group and unstable angina pectoris group were higher than those in normal group.HDLC was lower than that in normal group,HDL-C was respectively（1.08±0.36） mmol/L,（1.03±0.29） mmol/L vs（1.66±0.67） mmol/L.Abnormal rates of HDL-C,LDL-C and TC/HDL-C in stable angina pectoris group and unstable angina pectoris group had significant difference to those of normal group,respectively 36.9%,39.1% vs 20.0%,32.0%,32.8% vs 16.0%,65.6%,72.7% vs 38.6%.Conclusion TC/HDL-C ratio is a superior measure of risk for CHD compared with other single index of cholesterol.
出处
《临床荟萃》
CAS
2010年第19期1692-1693,共2页
Clinical Focus
