摘要
目的]研究轮叶党参水提取液对老年雌性小鼠的学习记忆能力的影响.[方法]采用水迷宫实验及测定脂质过氧化物的方法.[结果]经口给予4g/kg和8g/kg轮叶党参水提取液18d时,水迷宫试验中的平均潜伏期明显缩短,水迷宫试验的错误次数显著减少.[结论]给予轮叶党参组小鼠学习记忆速度较老年对照组快.
Objective To assay the effects of Codonopsis lanceolata on learning and memoryn in old female mice.Method The water maze test and the determination of lipid peroxide contents were used.Result Latent period in water maze test is statistically shorten and the numbers of errors are visibly reduced in the mice treated with drinking extract of Codonopsis lanceolata 4g/kg and 8g/kg for 18 days.Conclusion Mice drinking extract of Codonopsis lanceolata learn faster than those of old control.The contents of lipid peroxide in red blood cell and brain of mice drinking extract of Codonopsis lanceolata are significantly reduced.
出处
《延边大学医学学报》
CAS
1999年第1期31-33,共3页
Journal of Medical Science Yanbian University
关键词
党参
学习记忆
过氧化脂质
小鼠
中药
药理
Radix codonopsis pilosulae
learning
memory
lipid peroxides
mice