摘要
目的优选安乳颗粒中丹参的提取工艺。方法以丹参酮ⅡA的含量为考察指标,应用L9(34)正交试验法考察乙醇浓度、液料比、提取时间对提取效果的影响。结果影响因素依次是:乙醇浓度(A)>液料比(B)>提取时间(C),最佳制备工艺为A2B2C2,即加8倍量80%乙醇,加热回流提取2次,每次1.5h。结论该优选制备工艺合理,有效成分提出率高。
Objective To optimize the extracting procedure of Salvia miltiorrhiza in Anru keli.Methods TanshioneⅡA as a detective target,the optimum extracting conditions were studied by the orthogonal test of L9（34）.The experiment was involved three factors： alcohol concentration（A）,liquid-solid ratio（B）,extracting time（C）.Results The influencing effect of factors was as follows ABC.The optimizing preparation conditions were A2B2C2,that was 8 times 80% alcohol was added,and extracted 1.5h for two times.Conclusion The optimum preparation procedure is reliable and the extracting rate of active component is high.
出处
《中国药事》
CAS
2010年第8期744-746,共3页
Chinese Pharmaceutical Affairs
基金
甘肃省重大研发项目(编号GKS002-01-14)
甘肃省重点中医药科研项目(编号GZK-2009-11)
关键词
安乳颗粒
丹参
正交试验
丹参酮ⅡA
Anru keli
Salvia miltiorrhiza
orthogonal test
tanshinoneⅡA
