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不同卵泡刺激素在控制性超排卵中的对比性观察

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摘要 目的比较基因重组卵泡刺激素(r-FSH)和尿源性卵泡刺激素(u-FSH)在体外受精-胚胎移植(IVF-ET)和卵胞浆内单精子注射(ICSI)中控制性超排卵的效果。方法将128例接受IVF和ICSI的不孕患者分为r-FSH组76例,u-FSH52例,均采用黄体期长方案超排卵,卵泡监测、采卵、受精方式按本中心常规进行。观察两组患者卵泡刺激素的剂量、天数、费用及获卵数、卵裂率、优胚率、妊娠率、中重度卵巢过度刺激综合征的发生率。结果两组FSH总支数、获卵数、卵裂率、HCG日子宫内膜厚度、妊娠率比较,均无统计学意义(P>0.05),但r-FSH组药物费用高于u-FSH组。结论 u-FSH与r-FSH在超排卵中具有同样的有效性和安全性,且可以降低患者的经济负担。
作者 赵亚琼 杨芳
出处 《宁夏医学杂志》 CAS 2010年第8期719-720,共2页 Ningxia Medical Journal
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