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基因重组卵泡刺激素对PCOS不孕患者促排卵治疗的疗效观察(附96例分析) 被引量:3

Curative effect observation on polycystic ovary syndrome infertility treated with gene recombinant follicle stimulating hormone
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摘要 目的比较基因重组卵泡刺激素(r-FSH)和绝经后促性腺激素(HMG)对多囊卵巢综合征(P-COS)不孕患者促排卵治疗的疗效,评价r-FSH的治疗作用。方法将96例PCOS不孕症患者分为四组,22例给予克罗米酚(CC)加r-FSH单次联合给药,24例给予CC加HMG单次联合给药,26例用r-FSH低剂量缓增给药治疗,24例用HMG低剂量缓增给药治疗,观察各组疗效。结果应用r-FSH低剂量缓增给药相比其他三组有较高的临床妊娠率,而且相比同种治疗方案的HMG组所需治疗天数更少,所用总剂量更低。结论采用r-FSH低剂量缓增促排卵方案治疗不孕PCOS患者有较好疗效。 Objective To compare the effects of recombinant follicle stimulating hormone (r-FSH) and menotropins (HMG) on controlled ovarian stimulation for polycystic ovary syndrome infertility treated, evaluate therapeutic effect of r- FSH. Methods 96 cases of PCOS infertility patients were divided into four groups. 22 cases was treated with clomide (CC) plus r-FSH single administration, 24 cases was treated with clomide (CC) plus HMG single administration, 26 cases was treated with low dose-increasing r-FSH method, 24 cases was treated with low dose-increasing HMG method, observe the effects of each treatment. Results Application of r-FSH case by low dose increasing method have higher clinical pregnancy rate compared to other groups, taking for fewer days of treatment and using a lower total dose than the same treatment by HMG. Conclusion Low dose-increasing r-FSH method is a values treatment method for the PCOS infertility patients in controlled ovarian stimulation.
作者 苏艳华
出处 《福建医药杂志》 CAS 2008年第2期72-74,共3页 Fujian Medical Journal
关键词 多囊卵巢综合征 不孕症 促排卵 基因重组卵泡刺激素 Polycystic ovary syndrome Infertility Controlled ovarian stimulation Recombinant follicle stimulating hormone
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