摘要
目的:探讨不同病理亚型肺腺鳞癌的临床特点。方法:根据肺腺鳞癌2种成分的分布不同分为独立生长型和混合生长型;根据2种成分含量不同分为腺癌为主、腺鳞相当及鳞癌为主型。分析不同病理亚型肺腺鳞癌的临床表现和术后生存期,研究病理与临床之间的联系。结果:性别、年龄、吸烟情况、病程、症状、手术切除率及P-TNM分期与病理分型无明显相关性。腺癌为主的病例多为周围型,纤维支气管镜下多表现为浸润型或非典型改变,以鳞癌为主的病例多为中央型,在纤维支气管镜下多表现为新生物,以腺癌为主者纵膈淋巴结转移率较高。独立生长型较混合生长型生存时间长;腺癌为主者生存时间最短,其次为腺鳞相当者,鳞癌为主者生存时间最长。结论:肺腺鳞癌的病理分型与临床特征之间存在一定联系,掌握其相关性有利于对肺腺鳞癌的诊断及预后判断。
Objective To investigate the clinical features of different pathological subtypes of adenosquamous carcinoma of the lung.Methods Adenosquamous carcinoma of the lung was divided into independent growth pattern and mixed growth pattern according to the distribution of two different components.And adenosquamous carcinoma of the lung was divided into adenocarcinoma-predominant pattern,composition-comparative pattern and squamous carcinoma-predominant pattern according to the content of two different components.The clinical manifestation and postoperative survival time of different subtypes of adenosquamous carcinoma of the lung were analyzed,and the correlation was studied between pathology and clinical features.Results No significant correlation was found between pathological typing and gender,age,smoking,disease course,symptoms,surgical resection rate and P-TNM staging.Most cases of adenocarcinoma-predominant pattern were peripheral lung cancer,mainly displaying as infiltration or atypical changes under bronchoscopy,and most of squamous carcinoma-predominant pattern cases were central type lung cancer,mainly displaying as mass under bronchoscopy.The rate of mediastinal lymph node metastasis was higher in adenocarcinoma-predominant pattern than that in squamous carcinoma-predominant pattern.The survival time of independent growth pattern was longer than that of mixed growth pattern,and the survival time of adenocarcinoma-predominant pattern was the shortest,followed by composition-comparative pattern.The survival time of squamous carcinoma-predominant pattern was the longest.Conclusion Pathological typing is associated with the clinical feature in adenosquamous carcinoma of the lung.To study the correlation will contribute to the diagnosis and prognosis.
出处
《中华实用诊断与治疗杂志》
2010年第8期769-771,774,共4页
Journal of Chinese Practical Diagnosis and Therapy
关键词
肺腺鳞癌
病理类型
临床特征
生存时间
Adenosquamous carcinoma of the lung
pathological type
clinical feature
survival time
