摘要
1957～1991年间,治疗原发性支气管肺癌3568例,手术切除率90.3％,死亡率0.89％,术后并发症发生率8％。病理分型为:鳞癌48.7％,腺癌22.9％,小细胞癌15.4％,鳞腺癌10.1％,大细胞癌1.3％。本组病人失访250例,随访率为93％。切除术后5年生存率34.6％,10年生存率为23％。病理分期、组织类型以及纵隔淋巴结转移是影响预后的主要因素。本组Ⅲ期病人1251例,占42.6％,5年生存率:Ⅲa期19％,Ⅲb期6％。重点探讨了Ⅲ期病人的手术适应证,手术有关问题及综合治疗措施。
This paper summerized the surgical treatment of primary bronchogenic carcinoma in 3568 cases between 1957-1991. The resectability rate was 90. 3%, postoperative morbidity rate 8.32% and operative mortality 0. 89%. Pathological diagnoses of the resected specimens included squa-mous cell carcinoma for 48.7%, adenocarcinoma 22.9%, small cell cancer 15. 4%, large cell cancer 1. 3% and squa-mous-adenocarcinoma in 10.1%. The follow-up rate was 93%. The 5-and 10-year survival rates were 34.6% and 22.79% respectively. Analyses of the data demonstratad that the histologic type, pathological stage and metastasis of mediastinal lymph node are the important factors affecting the prognosis. According to UICC P-TNM,42. 6% of the patients in this group were in stage III. The 5 year survival rate was 19% in IIIa patients and 6% in IIIb. According to authors experience, it is recommended that in IIIa patients with nonsmall cell cardinoma, active surgical treatment should be adopted; in patients with small cell carcinoma, chemotherapy and radiotherapy should be given pre-and postoperatively, in IIIb patients with small cell carcinoma, surgical treatment is generally not indicated.
出处
《中华胸心血管外科杂志》
CSCD
北大核心
1995年第5期273-274,共2页
Chinese Journal of Thoracic and Cardiovascular Surgery
关键词
肺肿瘤
外科手术
手术适应证
Surgical treatment
Primary bronchogenic carci-noma
