摘要
目的：研究大叶石头花地上部分的黄酮碳苷成分。方法：用70%乙醇回流提取,氯仿和正丁醇依次萃取,采用硅胶、SephadexLH-20、ODS柱色谱等方法分离纯化,根据理化性质和光谱数据鉴定化合物的结构。结果：从大叶石头花地上部分分离得到6个黄酮碳苷：皂草黄素（isovitexin,1）,芒果素（mangiferin,2）,异荭草素（isoorientin,3）,2＇＇-O-鼠李糖基-7-甲氧基异荭草素（4）,2＇＇-O-鼠李糖基皂草黄素（5）,2＇＇-O-鼠李糖基异荭草素（6）。结论：化合物1~6首次从该属中分离得到。
AIM：To study the C-glycosylflavonoids from the aerial parts of Gypsophila pacifica Kom.METHODS：The C-glycosylflavonoids were isolated by various column chromatographic methods and their structures were identified by spectral data together with physicochemical analysis.RESULTS：Six known compounds were isolated and identified as isovitexin（1）,mangiferin（2）,isoorientin（3）,2＇＇-O-rhamnopyransoyl-7-methoxylisoorientin（4）,2＇＇-O-rhamnopyransoyl-isovitexin（5）,and 2＇＇-O-rhamnopyransoyl-isoorientin（6）.CONCLUSION：The six compounds were isolated from the genus Gypsophila for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
北大核心
2010年第4期250-252,共3页
基金
supported by the National Natural Science Foundation of China for Outstanding Young Scientists (No. 30525032)~~
关键词
大叶石头花
石竹科
黄酮碳苷
Gypsophila pacifica
Caryophyllaceae
C-Glycosylflavonoids
