摘要
目的:评价应用国产封堵器经导管治疗儿童大型动脉导管未闭的安全性及有效性。方法:12岁以下大型动脉导管未闭患儿66例,应用国产封堵器经导管进行介入治疗,于术后1、3、6月及每年进行超声心动图等随访,观察有无残余分流及主动脉狭窄等,评估该方法的效果及安全有效性。结果:技术成功率97%。应用目前最大封堵器失败转外科手术1例,由于重度肺动脉高压,试封堵后肺动脉压力无明显改善而放弃治疗1例。手术即刻残余分流率为23%,随访观察1月后为3%,6月后所有64例患儿均无残余分流。结论:国产封堵器经导管治疗儿童大型动脉导管未闭安全可行。
AIM： To evaluate the safety and efficacy of transcatheter closure of large patent ductus arteriosus （PDA） using domestic PDA occluders in children. METHODS： From July 2003 to July 2008, 66 children 〈12 years old with large PDA underwent attempted transcatheter closure using domestic PDA occluders. Patients were followed-up at 1, 3, 6, and 12 months and thereafter by electrocardiogram （ECG） and transthoracic echocardiography （TTE）. Complications including residual shunt and presence of aortic coarctation were observed. RESULTS： The overall technical success rate was 97%. One patient failed with the largest domestic PDA occluder and was treated with open surgery. Treatment was suspended in another patient with severe pulmonary hypertension because of the increased pulmonary pressure after attempted transcatheter occlusion. Instant residual shunt rates were 23% and 3% after 3 months and 0 after 6 months follow-up. CONCLUSION： Complications associated with transcatheter closure of PDA using domestic PDA occluders are relatively low in children. The procedure is safe and efficient and should become the treatment of choice for PDA patients.
出处
《心脏杂志》
CAS
2010年第4期595-597,606,共4页
Chinese Heart Journal
关键词
动脉导管未闭
介入治疗
超声心动描记术
经胸
patent ductus arteriosus
transcatheter intervention
transthoracic echocardiography
