摘要
目的 应用超声心动图评价 Amplatzer封堵器治疗成人动脉导管未闭 (PDA)术后左心功能的变化 .方法 6 8例成人 PDA (男 2 6例 ,女 4 2例 ) ,年龄 18～ 6 5 (32± 2 7)岁行Am platzer封堵器根治 PDA术 .应用超声心动图测量封堵前后左室舒张末期内径 (L VEDD)和收缩末期内径 (L VESD) .应用椭圆体体积法计算出左室舒张末期容积 (L VEDV)、收缩末期容积 (L VESV)、每搏搏出量 (L VSV)、射血分数 (L VEF)和短轴缩短率 (L VFS) ,将封堵前后测量数据分别用统计学配对 t检验 .结果 L VEDD,L VEDV,L VESV,L VSV封堵前分别 (6 0± 9) mm,(2 2 8± 90 ) m L,(5 4± 2 7) m L,(172± 74 )m L;封堵后 5 d分别降为 (5 0± 7) mm,(130± 6 0 ) m L,(41±2 1) m L ,(96± 4 5 ) m L (P<0 .0 5 ) ;封堵后 3mo分别为 (48±7) m m,(112± 5 0 ) m L ,(38± 17) m L ,(91± 4 0 ) m L (P<0 .0 5 ) ;L VEF,L VFS封堵前分别为 (5 6± 18) % ,(38± 5 ) % ;封堵后 5 d分别为 (5 1± 2 0 ) % ,(36± 6 ) % (P>0 .0 5 ) ,封堵后3mo分别为 (5 7± 8) % ,(38± 8) % .结论 Amplatzer封堵器治疗成人 PDA能缩短 L VEDD和改善左心功能 .
AIM To compare the changes of left ventricular function by transcatheter closure of adult patent ductus arte riosus(PDA) using the Amplatzer occluder. METHODS The inner diameters of the left ventricular on end diastole and end systole before and after transcatheter closure were measured by echocardiography in 68 adult cases of PDA(male 26, female 42) at a median age of 32±27 (range 18~ 60). Left ventricular endiastolic volume (LVEDV), left ventricular end systolic volume (LVESV), left ventricular stroke volume (LVSV), left ventricular ejection fraction (LVEF) and left ventricular fraction shortening (LVFS) were calculated by prolate ellipse formula automatically. Then the figures were statistically disposed by t test. RESULTS LVEDV, LVESV, LVSV after transcatheter closure decreased to normal (50±7) mm,(130±60) mL,(41±21) mL,(96±45) mL 5 d after catheter closure; (48±7) mm,(112±50) mL, (38± 17) mL,(91±40) mL 3 mo after catheter closure in comparison with those before transcatheter closure [(60±9) mm,(228±90) mL,(54±27) mL,(172±74) mL respectively], with significant difference ( P <0.05), but there were no significant difference in LVEF and LVFS after catheter closure. CONCLUSION Transcatheter closure of adult PDA using Amplatzer occluder can greatly improve left ventricular function.
出处
《第四军医大学学报》
北大核心
2002年第14期1321-1322,共2页
Journal of the Fourth Military Medical University
