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CD34和HLA-DR在初治成人急性髓细胞白血病中的表达及意义 被引量:3

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摘要 目的:研究CD34和HLA-DR在初治成人急性髓细胞白血病(M3除外)中的表达及意义。方法:应用流式细胞术测定初治成人急性髓细胞白血病患者骨髓细胞膜上CD34和HLA-DR的表达。结果:急性髓细胞白血病患者CD34、HLA-DR表达的阳性率分别为67.6%(96/142),74.6%(106/142);CD34,HLA-DR阳性表达组缓解率低于阴性表达组(P<0.05);CD34/HLA-DR双阳性表达组缓解率低于双阴性表达组(P<0.05)。结论:CD34、HLA-DR在急性髓细胞白血病患者骨髓细胞中阳性表达率高,且阳性表达者完全缓解率低,提示预后不良。
作者 陈黎 孙慧
出处 《中华实用诊断与治疗杂志》 2010年第7期707-708,共2页 Journal of Chinese Practical Diagnosis and Therapy
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