摘要
目的 探讨疏血通注射液治疗急性脑梗死患者的疗效及对血清C反应蛋白（CRP）的影响.方法 选择发病48 h内的急性脑梗死患者120例.按照随机数字表法分为治疗组和对照组（各60例）,两组患者视病情轻重及并发症给予对症治疗,其中治疗组给予疏血通6mL静脉滴注,对照组给予安慰剂曲克芦丁入液静滴,每天1次,疗程均为14d.采用免疫散射速率比浊法测定两组患者治疗前及治疗后第5天、第10天、第14天血清CRP浓度,并观察两组患者治疗前及治疗后14d时临床神经功能缺损程度评分.结果治疗组治疗后第5天、第10天、第14天血清CRP浓度与对照组比较差异均有统计学意义（P〈0.05）.治疗组患者治疗后14 d时神经功能缺损评分为14.57±7.88,明显低于对照组（19.08±8.11）,比较差异有统计学意义（P〈0.05）.结论 疏血通注射液有降低急性脑梗死患者血清CRP浓度、改善神经功能的作用.
Objective To observe the curative effects of Shuxuetong in treating patients with acute cerebral infarction and its effects on the level of serum C-reactive protein （CRP）.Methods One hundred and twenty patients with acute cerebral infarction who had the onset within 48 h were equally randomized into treatment group and control group.Six ml Shuxuetong and Troxerutin for intravenous drip daily were given to the treatment group and the control group,respectively,for a consecutive 14 d.The concentrations of serum CRP in the 2 groups were measured by immunonephelometry before treatment and on the 5th,10th and 14th d of treatment.The scores of neurological functional deficit scale were compared before treatment and on the 14th d of treatment in the 2 groups.Results The concentration of serum CRP in the treatment group on the 5th,10th and 14th d of treatment was significantly lower than that in the control group （P〈0.05）.The scores of neurological functional deficit scale in the treatment group （14.57±7.88） were significantly lower than those in the control group （19.08±8.11） （P〈0.05）.The clinical efficacy between the 2 groups was obviously different （P〈0.05）.Conclusion Shuxuetoug can decrease the concentration of serum CRP and improve the nervous function in patients with acute cerebral infarction.
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2010年第6期619-621,共3页
Chinese Journal of Neuromedicine
关键词
脑梗死
C反应蛋白
疏血通
Cerebral infaction
C-reactive protein
Shuxuetong
