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血浆B型脑钠肽和氧化应激水平变化与慢性心力衰竭严重程度相关性的研究 被引量:3

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摘要 目的探讨血浆B型脑钠肽(BNP)和氧化应激水平变化与慢性心力衰竭(CHF)严重程度的相关性。方法选择2008年6月至2009年6月我院收治的CHF患者101例,并选择同期体检者21例作为对照组,测定2组总抗氧化物(TAS)、过氧化脂质(LPO)及BNP水平,分析血清TAS、LPO和BNP水平变化与心力衰竭严重程度的相关性。结果不同级别心力衰竭组之间比较,随着心力衰竭度的增加,血清TAS水平明显降低,BNP和LPO明显升高,均有统计学意义(P<0.05),血清TAS与BNP和LPO均呈负相关(r=-0.910,P=0.0002;r=-0.859,P=0.000),而BNP与LPO呈正相关(r=0.956,P=0.0004)。结论血清TAS、LPO和BNP水平变化与心力衰竭严重程度具有良好相关性。
出处 《河北医药》 CAS 2010年第6期669-670,共2页 Hebei Medical Journal
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参考文献8

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