摘要
目的探讨慢性充血性心力衰竭(CHF)患者血红蛋白(Hb)水平的变化、与心功能关系及其对CHF患者预后的影响。方法入选CHF患者178例,参照NYHA分级分为2组,心功能Ⅰ～Ⅱ级(轻中度组)85例,Ⅲ～Ⅳ级(重度组)93例。比较2组Hb水平等血液学参数和贫血发生率,并对贫血组和非贫血组在随访期间心血管事件指标进行分析。结果178例CHF患者中贫血(血红蛋白<120g/L)45例(25.28%),其中重度组中贫血31例(33.33%),明显多于轻中度组14例(16.47%,P<0.01)。随访期间贫血组与非贫血组再住院率(33.33%∶15.04%)、病死率(26.67%∶10.53%)比较,差异有统计学意义(P<0.01)。结论CHF患者常伴有贫血,贫血的程度与CHF严重程度有关,Hb水平降低可预测CHF患者的预后。
Objective To investigate the change of hemoglobin （Hb） concentration, its correlation with NYHA-elass and its effect on the prognosis of patients with chronic heart failure（CHF）. Methods 178 patients with CHF were divided into two groups according to NYHA：85 patients in mild and medium degree CHF group （cardiac function class Ⅰ - Ⅱ ） ; 93 patients in severe degree CHF group （ cardiac function class Ⅲ-Ⅳ ）. Hematology data including Hb levels and the incidence of anemia were detected and compared in 2 groups, and the cardiovascular events in anemia group and non-anemia group were analyzed during follow-up. Results Among 178 patients with CHF, anemia （ HB 〈 120 g/L） presented in 45 patients（25.28% ）in which 31 cases（33.33% ） in severe degree CHF group were significantly higher than those （14 cases, 16.47% ） in mild and medium degree CHF group （ P 〈 0. 01 ）. There was a significant difference in rehospitalization rate between anemia group and non-anemia group（33.33% vs 5.04%, P 〈 0. 01 ）, and there was a significant difference in mortality between anemia group and non-anemia group （26.67% vs 10.53%, P 〈0.01 ）. Conclusion The change of Hb levels is closely correlated with the prognosis of patients with CHF.
出处
《河北医药》
CAS
2009年第9期1045-1047,共3页
Hebei Medical Journal
关键词
慢性心力衰竭
贫血
血红蛋白
预后
chronic heart failure
anemia
hemoglobin
prognosis
