摘要
目的:考察曲克芦丁在聚氯乙烯(PVC)输液器中的吸附情况。方法:分别将0.9%氯化钠注射液、5%葡萄糖注射液与曲克芦丁注射液混合(0.9%NS组、5%GS组),模拟临床静脉滴注,流经PVC输液器,在24h内不同时间段收集流出的样品,测pH值,用高效液相色谱法测定样品含量,并分别与流经输液器前的结果进行比较。结果:0.9%NS组与5%GS组流经输液器前、后24h内,pH值及含量均无明显变化(P>0.05)。结论:在本试验条件下,PVC输液器对曲克芦丁未见吸附作用。
usion system of polyvinyl chloride （PVC）. METHODS： In 0.9% NS group 0.9% sodium chloride injection was mixed with troxerutin injection while in 5%GS group 5% glucose mixed with troxerutin injection. Mixtures were injected intravenously using PVC infusion systems. Samples were collected at different time points within 24 h and their pH values were measured. The content of samples were determined by HPLC and compared with the results of before infusion. RESULTS： There was no significant difference in pH value and content of samples within 24 h before and after infusion in both groups （P〉0.05）. CONCLUSION： In the study, PVC infusion systems have no adsorption effect on troxerutin.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第13期1182-1183,共2页
China Pharmacy
关键词
曲克芦丁
聚氯乙烯输液器
吸附
高效液相色谱法
Troxerutin
Infusion system of polyvinyl chloride
Absorption
HPLC methods
