摘要
目的:探讨β-绒毛膜促性腺激素(β-HCG)水平与药物流产结局的相关性。方法:选择停经≤49d已确诊早孕,要求用药物(米非司酮配伍米索前列醇)流产的妇女85例,其中完全流产47例,不完全流产33例。检测药物流产前及药物流产后3 d,7 d,14 d,21 d药流妇女血清β-HCG水平。结果:药流后第3天血清β-HCG水平在完全流产组与不完全流产组之间均有明显降低(P<0.05),但组间比较,差异无统计学意义(P>0.05);药流后7 d完全流产组β-HCG水平继续降低,与不完全流产组组间比较,差异有统计学意义(P<0.05);药流后14 d完全流产组β-HCG水平降至接近正常值,与不完全流产组比较,差异有统计学意义(P<0.01);药流后21 d完全流产组β-HCG水平降至正常值水平。结论:血清β-HCG水平直接反映药物流产的结局,在3周内β-HCG水平回复正常的,表示药流完全。
Objective To study the relationship between β-HCG level and outcome of drug abortion.Method The serum β-HCG levels of 85 early pregnancy women who had terminated their pregnancy by administration of mifepristone and misoprostol（47 cases of complete abortion and 33 cases of incomplete abortion） were detected on the 3rd,7th,14th and 21th day after discharging pregnant.Results On the 3rd day,the β-HCG level in complete and incomplete abortion groups were both decreased（P0.05）,but there was no significant difference between the two groups（P0.05）;on the 7th day,the β-HCG level of complete abortion group was continuously decreased,and there was significant difference compared with incomplete abortion group（P0.05）;on the 14th day,the β-HCG level in complete abortion group was close to the normal,and there was higher significant difference compared with incomplete abortion group（P0.01）;on the 21th day,the β-HCG level in complete abortion group was recovered to the normal.Conclusion The level of β-HCG in serum could directly reflect the outcome of drug abortion.The level of β-HCG in serum recovers to the normal in 3 weeks means the drug abortion is complete.
出处
《吉林医学》
CAS
2010年第7期880-882,共3页
Jilin Medical Journal
