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非ST段抬高型急性冠脉综合征肌钙蛋白Ⅰ水平对危险分层的评估 被引量:3

Risk assessment value of troponin I in patients with non-ST-segment elevation acute coronary syndrome
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摘要 目的:探讨血清肌钙蛋白Ⅰ(cTnI)对非ST段抬高型急性冠状动脉综合征(NSTEACS)患者危险分层的判断价值。方法:对82例NSTEACS患者、50例健康者分别进行血清cTnI测定,并观察NSTEACS患者住院1个月内心脏事件发生情况。结果:NSTEACS组血清cTnI值明显高于正常对照组(P<0.01)。NSTEACS组内,心肌梗塞者(cTnI阳性亚组)血清cTnI值明显高于不稳定型心绞痛者(cTnI阴性亚组)(P<0.01)。正常对照组无一例发生心脏事件;cTnI阳性亚组心脏事件发生率为17.3%,显著高于cTnI阴性亚组的5.5%(P<0.05)。结论:血清cTnI水平对NSTEACS患者危险分层有较好的价值。 Objective:To evaluate the value of serum troponin I (cTnI)in risk stratification of patients with non-ST-segment elevation acute coronary syndrome(NSTEACS).Methods:Serum cTnI levels were measured in 50 healthy subjects(control group),and 82 NSTEACS patients respectively.Cardiac events(cardiac sudden death)were observed within l month of hospitalization.Serum cTnI≥1.5μg/L was considered as the cut off level for myocardial damage.Results:Serum cTnI levels in the NSTEACS group were higher than that in the control group[(1.98±0.11)μg/L vs.(0.49±0.10)μg/L,P〈0.01].In the NSTEACS group,serum cTnI levels in the non-ST-segment elevation acute myocardial infarct (NSTEMI) group were higher than that in the UAP group(P〈0.01).No cardiac events happened in the control group;in the NSTEMI(cTnI≥1.5μg/L) and UAP group(cTnI〈1.5μg/L),the rate of cardiac events was (17.3%vs.5.5%,P〈0.05).Conclusion:The serum cTnI level has clinical value in risk assessment of patients with non-ST-segment elevation acute coronary syndrome.
出处 《心血管康复医学杂志》 CAS 2010年第1期31-32,共2页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 肌钙蛋白I 冠状动脉疾病 危险性评估 Troponin I Coronary artery disease Risk assessment
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