摘要
目的:探讨瘦素(Leptin)与子宫内膜异位症发病的关系。方法:采用抗生物素蛋白-过氧化物酶(SP)法对子宫内膜异位症患者的在位和异位子宫内膜(各30例)进行瘦素检测,取30例正常子宫内膜作对照。结果:正常子宫内膜和内异症在位及异位内膜中均有瘦素表达,在位内膜中Leptin表达强于对照组子宫内膜(P<0.05)。结论:瘦素可能对子宫内膜异位症的发生、发展起促进作用。
Objective ： To explore the relationship between leptin and pathogenesis of endometriosis. Methods： The levels of leptin in ectopie endometrium and eutopie endometrium from 30 cases with endometriosis and eutopic endometrium from 30 cases without endometriosis were detected by immunohistochemieal assay. Results： Leptin expressed in ectopic endometrium and eutopie endometrium from 30 cases with endometriosis and eutopic endometrium from 30 cases without endometriosis, the level of leptin in eutopic endometrium from 30 cases with endometriosis was significantly higher than that from 30 cases without endometriosis （P 〈 0. 05 ） . Conclusion： Leptin may promote the occurrence and development of endometriosis.
出处
《中国妇幼保健》
CAS
北大核心
2010年第4期545-547,共3页
Maternal and Child Health Care of China
关键词
子宫内膜异位症
在位内膜
瘦素
免疫组化
Endometriosis
Eutopic endometrium
Leptin
Immunohistochemistry
