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瘦素及其受体在子宫内膜异位症中表达的意义 被引量:2

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摘要 子宫内膜异位症(endometriosis,EMs)是生育年龄常见的一种良性病变,但具有类似恶性肿瘤的种植、侵蚀及远处转移的能力,严重影响育龄妇女的生育能力和生活质量。近年来随着腹腔镜技术及检测手段的不断改进,EMs发病率呈明显上升趋势。其发病机制、病因尚未完全阐明,已有研究表明其发生与遗传、免疫、炎症反应等因素有关,特别是其作为一种与免疫相关的慢性炎症疾病,表现为促血管生成和影响炎性因子分泌增加。
出处 《浙江临床医学》 2012年第3期312-313,共2页 Zhejiang Clinical Medical Journal
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参考文献6

  • 1Cava A, Alviggi C, Metarese G, et al. Unraveling the multiple roles of leptin in flammation and auto immumity. Mtl Med ,2004,82:4 ~ 11. 被引量:1
  • 2Matarese G, Sanna V, Fontana S, et al. Leptin as a novel therapeutic target for immune intervention. J Curr Drug Targets Inflamm Allergy, 2002,1 : 13 ~ 22. 被引量:1
  • 3Tanaka T, Utsunomiya T, Bai T, et al. Lepin inhibits decidualization and enhances cell viability of normal human endometrial stromal. J Mol Med,2003,12 ( 1 ) :95 ~ 98. 被引量:1
  • 4Wu MH,Chuang PC, Chen HM, et al. Increased Lepin expression in endometriosis cells is associated with endometrial stromal cell prolifer- ation and lepin gene up - regulation. J Mol Hum Reprod, 2002,8 (5) :456 ~464. 被引量:1
  • 5Wertel I, Gogacz M, Polak G,et al. Lepin is not involved in the path- physiology of endometriosis - related infertility. Obstet Gynecol Re- prod,2005,119 ( 2 ) :206 N 209. 被引量:1
  • 6魏晓强,张怡,唐猛,彭丽秀.子宫内膜异位症血清及腹腔液瘦素水平的比较分析[J].实用妇产科杂志,2006,22(1):34-36. 被引量:6

二级参考文献8

  • 1America Fertility Society.Revised Amecican Fertility sociery classification of endometriosis:1985.Fertil Steril,1985,43:351-354. 被引量:1
  • 2Bouloumie A,Drexler HC,Lafontan M,et al.Leptin,the product of Ob gene,promotes angiogenesis.Circ Res,1998,83(10):1059-1066. 被引量:1
  • 3Cao R,Brakenhielm E,Wahlestedt C,et al.Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF.Proc Natl Acad Sci U S A.2001,98(11):6390-6395. 被引量:1
  • 4Tanaka T,Utsunomiya T,Bai T,et al.Leptin inhibits decidualization and enhances cell viability of normal human endometrial stromal cells.Int J Mol Med,2003,12(1):95-98. 被引量:1
  • 5Lord GM,Matarese G,Howard JK,et al.Leptin modulates the T-cell inmmune response and reverse starvation-induced immunosuppression.Nature,1998,394(6696):897-901. 被引量:1
  • 6Santos-Alvarez J,Goberna R,Sanchez-Margalet V.Human leptin stimulates proliferation and activation of human circulating monocytes.Cellular Immunology,1999,194(1):6-11. 被引量:1
  • 7Wu MH,Chuang PC,Chen HM,et al.Increased leptin expression in endometriosis cells is associated with endometrial stromal cell proliferation and leptin gene up-regulation.Mol.Hum.Reprod,2002,8(5):456-464. 被引量:1
  • 8陈骞,唐海峰,李尚为.瘦素与女性不孕[J].国外医学(计划生育分册),2003,22(4):230-233. 被引量:6

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同被引文献32

  • 1樊丽萍.丙酸睾丸酮配伍米非司酮、米索前列醇药物终止10-16周妊娠的临床观察.中国医师杂志,2011,2(z2):134-135. 被引量:1
  • 2Gouya H, Oudjit A, Leconte M, et al. CT antegrade colonography to assess proctectomy and temporary diverting ileostomy complica- tions before early ileostomy takedown in patients with low rectal endometfiosis. AJR Am J Roentgeno1,2012,198 ( 1 ) :98-105. 被引量:1
  • 3Alvarez P,Bogen O,Chen X,et al.Ectopic endometrium-derived leptin produces estrogen-dependent chronic pain in a rat model of endometriosis.neuroscience:An International Journal under the Editorial Direction of IBRO,2014(258):111-120. 被引量:1
  • 4Oh HK,Choi YS,Yang Y-I,et al.Leptin receptor is induced in endometriosis and leptin stimulates the growth of endometriotic epithelial cells through the JAK2/STAT3 and ERK pathways.Molecular Human Reproduction,2013,19(3/4):160-168. 被引量:1
  • 5Shah DK,Correia KF,Harris HR,et al.Plasma adipokines and endometriosis risk:A prospective nested case-control investigation from the Nurses’Health Study II.Human Reproduction,2013,28(2):315-321. 被引量:1
  • 6Malhotra N,Karmakar D,Tripathi V,et al.Correlation of angiogenic cytokines-leptin and IL-8 in stage,type and presentation of endometriosis.Gynecological endocrinology:the official journal of the International Society of Gynecological Endocrinology,2012,28(3):224-227. 被引量:1
  • 7Carmona F,Chapron C,Martínez-Zamora MA,et al.Ovarian endometrioma but not deep infiltrating endometriosis is associated with increased serum levels of interleukin-8 and interleukin-6.Journal of Reproductive Immunology,2012,95(1/2):80-86. 被引量:1
  • 8Rocha ALL,Carrarelli P,Novembri R,et al.Activin A stimulates interleukin 8 and vascular endothelial growth factor release from cultured human endometrial stromal cells:Possible implications for the pathogenesis of endometriosis.Reproductive sciences,2012,19(8):832-838. 被引量:1
  • 9杨丽芬,朱春林,徐琼芬.子宫内膜异位症术后丹莪妇康煎膏及米非司酮辅助治疗的临床观察[J].中国医学创新,2010,7(10):52-53. 被引量:4
  • 10蓝海燕.三种方法治疗卵巢子宫内膜异位囊肿对卵巢功能的影响[J].国际医药卫生导报,2011,17(3):295-297. 被引量:24

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