摘要
目的了解注射用头孢哌酮钠舒巴坦钠不良反应/事件发生的相关因素。方法采用回顾性研究方法,对2007年1月至2009年4月淄博市药品不良反应监测中心收集的184例注射用头孢哌酮钠舒巴坦钠不良反应/事件报告进行统计分析。结果不良反应/事件以0～10岁儿童发生率最高,主要表现为皮肤及其附件、消化系统、呼吸系统及全身性损害。多数不良反应/事件出现在用药后30分钟内,且以联合用药出现不良反应/事件的症状较重。结论应加强注射用头孢哌酮钠舒巴坦钠用药监护,减少不良反应/事件的发生。
Objective To analyze relevant factors of the adverse drug reaction/event（ADR/ADE） induced by cefoperazone sodium and sulbactam sodium for injection. Methods 184 ADR/ADE reports of cefoperazone sodium and sulbactam sodium for injection collected by Zibo Center for ADR Monitoring from January 2007 to April 2009 have been analyzed retrospectively. Results The children that were one to ten years old had higher probability of ADR/ADE occurrence. The clinical manifestations of ADR/ADE involved skin and appendages damage, digestive system damage, respiratory system damage and system damage. Most ADR/ADE cases happened in 30 minutes after medicationand, and drug combination maybe cause serious adverse reactions.Conclusion In order to avoid occurrence of ADR/ADE, the patients should be intensively warded when they use cefoperazone sodium and sulbactam sodium for injection.
出处
《中国药物警戒》
2009年第12期746-750,共5页
Chinese Journal of Pharmacovigilance
关键词
注射用头孢哌酮钠舒巴坦钠
不良反应/事件
统计分析
cefoperazone sodium and sulbactam sodium for injection
adverse drug reaction/event （ADR/ADE）
analysis
