摘要
目的:调查儿科住院患者抗菌药物使用情况,为临床合理用药提供参考。方法:回顾性调查我院儿科2011年1–6月1289份出院患者抗菌药物的应用情况,采用Excel表对患者基本情况、抗菌药物使用情况、病原学送检情况、转归、不良反应、院内感染等方面进行汇总。结果:抗菌药物使用率为98.1%,以静脉滴注为主(96.6%),联合用药率为25.2%。其中,青霉素类、头孢菌素类和大环内酯类药物使用率分别为39.2%、37.9%和18.6%;头孢呋辛酯、阿莫西林/克拉维酸钾、阿奇霉素的用药频次分别居前3位。联合用药集中在大环内酯类和β内酰胺类抗菌药物。病原学送检率不足3%。结论:我院儿科抗菌药物使用在用药指征、品种选择、联合用药、给药频次、溶媒选择等方面存在不合理现象,需加强管理。
Objective： To investigate the application of antibacterials in pediatric inpatients and provide reference for clinical rational drug use. Methods： 1289 pediatric medical records in our hospital from January to June 2011 were selected and the use of antibacterials was analyzed retrospectively. The basic situation of patients, use of antibacterials, pathogenic examination, outcomes, adverse drug reaction and nosocomial infection were analyzed by Excel software. Results： The application rate of antibacterials was 98.1%, in which 96.6% was administered by intravenous drip, and the rate of combination use of antimicrobials was 25.2%. The percent of prescribing penicillins, cephalosporins, and macrolides were 39.2%, 37.9% and 18.6% respectively, and cefuroxime axetil, amoxicillin/clavulanate potassium and azithromycin ranked top 3 in terms of use frequency. The combination use of antibacterials focused on macrolides combined with beta-lactam antibiotics. The inspection rate of pathogenic bacteria was less than 3%. Conclusion： Clinical management of rational use of antibacterials must be enhanced, because the application of antibacterials had unreasonable problems in terms of indications, drug selection, combination therapy, frequency of medication, improper solvent selection.
出处
《中国药物应用与监测》
CAS
2012年第6期348-350,共3页
Chinese Journal of Drug Application and Monitoring
关键词
儿科
抗菌药物
合理用药
Pediatrics
Antibacterials
Rational drug use
