摘要
铊(Tl)是剧毒的重金属元素,会对生态环境和人体健康造成威胁。目前各国铊的环境安全标准存在差异。本文利用泥鳅红细胞微核技术,研究泥鳅Misgurnus anguillicaudatus红细胞微核率和核异常率与铊污染时间的关系,为该技术在铊毒理研究中的可行性和铊环境安全标准提供依据。结果表明:水体铊质量浓度为0.5μg·L-1下,随处理时间的延长,泥鳅红细胞微核率、核异常率显著增加,并与时间呈显著的正相关,其中微核率、核异常率分别在处理24h和48h时达到最大值;随后两指标逐步下降,与时间呈显著的负相关。在此铊质量浓度和处理时间内,核异常率与微核率均显著高于空白无铊对照处理,表明水体铊质量浓度0.5μg·L-1对泥鳅血红细胞具有遗传毒性。
Thallium （Tl） is a toxic heavy metal. Water pollution of thallium released from thallium-con-taining mines will result the possible adverse environment effects and human health problems. But the current drinking water standards of thallium are different in many countries. In order to prove the reason-able and scientificalness of water standards of thallium,the relationships between genotoxicity of thallium andtime on Misgurnus anguillicaudatus peripheral red blood cells are studied. The results show that red blood cell micronuclei and abnormal nuclei rise companied by the treatment time increasing when thallium content is 0.5 μg·L^-1 in water. Especially,frequencies of micronucleus and abnormal nucleus reach respectively the highest level after Misgurnus anguillicaudatus were treated by thallium 24 hours and 48 hours. And the correlations between the frequencies of those and treatment time are positive significantly. When Misgurnus anguillicaudatus were treated by 0.5 μg·L^-1 thallium in water from 6 to 96 hours,the frequency of red blood cell micronuclei and abnormal nuclei are significantly higher than those of control sample. That indicates that 0.5 μg·L^-1 thallium in water has genotoxicity on Misgurnus anguillicaudatus peripheral red blood cells on some degree.
出处
《生态环境学报》
CSCD
北大核心
2009年第5期1665-1668,共4页
Ecology and Environmental Sciences
基金
国家自然科学基金委-广东省人民政府联合基金项目(U0633001)
广州市属高校科技计划项目(62066)
关键词
铊
泥鳅红细胞
微核
核异常
时间
相关分析
thallium Misgurnus anguillicaudatus peripheral red blood cells micronucleus abnormal nucleus time correlation analysis
