摘要
目的探讨腮腺核素动态显像与自身抗SSA/SSB抗体检测对干燥综合征的诊断价值。方法对36例干燥综合征和45例非干燥综合征患者均进行腮腺核素动态显像及自身抗SSA/SSB抗体的检测,比较两种方法的灵敏度及特异性,并进行一致性分析。结果腮腺核素动态显像的灵敏度为86.1%,特异性为66.7%,自身抗SSA/SSB抗体检测的灵敏度为80.6%,特异性为66.7%,两者比较差异无统计学意义(P>0.05);且两种方法之间存在一致性(P=0.022),但一致性较差(Kappa=0.256)。结论腮腺核素动态显像与自身抗SSA/SSB抗体检测在诊断干燥综合征时具有相近的准确性,但两种方法的一致性较差,临床诊断干燥综合征时还需结合其他检查,综合判断。
Objective To investigate the diagnostic value of parotid radionuclide dynamic imaging and detection of autoantibodies （SSA/SSB antibody） in Sjogren＇s syndrome. Methods Radionuclide dynamic imaging and detection of autoantibodies （SSA/SSB antibody） were conducted on 36 patients with Sjogren＇s syndrome and 45 normal subjects without the disease. The sensitivity and specificity of two methods were compared, and the consistency analysis was performed. Results The sensitivity and specificity of parotid radionuclidc dynamic imaging were 86.1% and 66.7% respectively, while these of detection of autoantibodies （SSA/SSB antibody） were 80.6 % and 66.7% respectively. Two methods were of no significant difference statistically （P〉0.05）. Consistency of two methods was poor （P=0. 022, Kappa =0. 256）. Conclusion Both radionuclide dynamic imaging and detection of autoantibodies （SSA/SSB antibody） have the similar accuracy in diagnosis of Sjogren＇s syndrome, but the concordance of two methods is poor, so the diagnosis of Sjogren＇s syndrome may need combination with other techniques.
出处
《福建医药杂志》
CAS
2009年第5期91-92,共2页
Fujian Medical Journal
