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血清免疫球蛋白游离轻链测定在浆细胞疾病中的应用 被引量:1

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摘要 血清免疫球蛋白游离轻链κ和λ水平测定是多发性骨髓瘤和相关浆细胞疾病诊断和处理中的重要工具。血清免疫球蛋白游离轻链分析与血清蛋白电泳和免疫固定电泳联合可明显提高浆细胞疾病诊断的敏感性,并在除轻链淀粉样变性外的其他疾病中替代24h尿液检查。基础血清免疫球蛋白游离轻链可预测各种浆细胞病的预后。对轻链淀粉样变性、寡分泌型和非分泌型骨髓瘤,可通过血清免疫球蛋白游离轻链分析进行定量监测。对轻链淀粉样变性,连续血清免疫球蛋白游离轻链检测优于蛋白电泳和免疫固定电泳。
出处 《中华实用诊断与治疗杂志》 2009年第9期833-836,共4页 Journal of Chinese Practical Diagnosis and Therapy
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