摘要
目的:探讨长期大量饮酒所致肝细胞受损、变性、坏死所致酒精性肝硬变的临床特征。方法:回顾性分析本院消化科自2002年10月至2007年10月5年间诊断为酒精性肝硬变的住院患者临床资料,酒精性肝硬变患者为观察组,肝炎后肝硬变者为对照组。结果:观察组中乏力、纳差、肝区疼痛、肝大、腹腔积液、血清AST、GGT、ALP检测值明显高于对照组;脾脏增大者低于对照组;腹胀、肝掌、蜘蛛痣与对照组无显著差异。结论:酒精性肝硬变者与肝炎后肝硬变者相比,更容易出现乏力纳差等临床症状,转氨酶升高明显,肝脏合成功能受损,在保肝治疗时严格戒酒,才能达到良好的治疗效果。
Objective： To evaluate the clinical characteristics of alcoholic hepatocirrhosis induced by hepatic cells damage and degeneration. Methods： The clinical datum of in-patients who diagnosed alcoholic hepatocirrhosis from the October of 2002 to October of 2007 were analyzed and studied. Results： The rates of weakness, anepithymia, hepatlgia, enlargement of the liver, hydroperitoneum and the levels of AST, GGT and ALP were higher in the observation group than that in the control group. The rate of splenomegalia was lower in the observation group than that in the control group. There were no significant difference in abdominal distension, palmar erythemas and spider angioma, levels between observation group and control group. Conclusions： The daily alcohol intake and drink years of alcoholic hepatocirrhosis patients were correlated positively with hepatic damage. To achieve perfect treatment affect need temperance and therapeutics of liver-protection together.
出处
《湖南中医药大学学报》
CAS
2009年第7期7-8,11,共3页
Journal of Hunan University of Chinese Medicine
关键词
酒精
肝硬变
肝细胞
酒精性肝病
alcohol, hepatocirrhosis, hepatic cell, alcoholic liver disease
