摘要
提出了新一代喹诺酮类抗菌药氧氟沙星的高效液相色谱分析方法。以H3PO4-NH4H2PO4缓冲溶液(内加离子对试剂四乙基溴化铵)和甲醇为流动相,在ODS柱上成功地对氧氟沙星进行了分析。方法重现性好,氧氟沙星的相对偏差小于0.58%,回收率大于99.30%。
A method for determining quinolone antibacterial agent ofloxacin.With high-performance liquid chromatography on a reversed-phase column is presented.Quantitative and reproducible determination were possible for ofloxacin over the concentration ranges 0.5-75μg/ml.The recovery of ofloxacin was larger than 99.30% and the relative standard deviation was 0.58%.
出处
《郑州工业大学学报》
1998年第3期76-78,共3页
Journal of Zhengzhou University of Technology