摘要
目的探讨拉萨地区泌尿生殖系统支原体感染及耐药状况,指导临床合理用药。方法对拉萨地区326例疑似患者的分泌物进行支原体培养及药敏试验。结果支原体感染者158例,阳性率为48.46%;解脲支原体(Uu)、人型支原体(Mh)、混合感染(Uu+Mh)检出率分别为71.52%、8.86%和19.62%,Uu检出率显著高于Mh及Uu+Mh混合感染(P<0.05);支原体对美满霉素和强力霉素敏感性最强,其次为阿奇霉素、交沙霉素,对罗红霉素、氧氟沙星、左氧沙星敏感性较差。结论各型支原体耐药谱大致相同,Mh和Uu+Mh混合感染对部分抗生素的耐药性增强。
Objective To investigate the status of urogenital mycoplasma infection and antibiotic resistance and to guide rational drug use in Lasa area. Methods In vitro method was used to determine the infection rate and antibiotic resistance of Ureaplasma urealyticum （Uu） and mycoplasma hominis（Mh） in the 326 suspected cases. Results The clinical isolates was 158 and the mycoplasma infection rate was 48.46 %, with Uu 71.52 %, Mh 8.86 % and mixed infection 19.62 %, respectively. The Constituent ratio of Uu was prominently higher than that of Mh and mixed infection （ P 〈 0.05）. The antibioctic susceptibility test showed that the most sensitive antibiotics were minocin and doxyeycline, following by azithromyein and josamycin. Meanwhile, roxithromycin, ofloxaein and levofloxaein showed remarkable resistance. Conclusion Basically parallel antimierobial spectrum was shared by subtypes of myeoplasma. It seems mycoplasma hominis and mixed infection would aggravate the phenomenon of antibiotic resistance.
出处
《中国实验诊断学》
北大核心
2009年第8期1073-1075,共3页
Chinese Journal of Laboratory Diagnosis
关键词
支原体
药敏试验
非淋菌性尿道(宫颈)炎
抗生素耐药
Mycoplasma
antibiotic susceptibility test
non-gonoccocal urethritis/cervicitis（NCU）
antibiotic resistance
