摘要
目的:调查我院常见G—致病菌的种类及其对目前常用抗生素的耐药现状,为临床医生合理选用抗生素提供数据资料。方法:从3286个样本中分离到742株G—致病菌,用全自动微生物分析仪--VITEK 32进行菌种鉴定及药敏实验。结果:742株G—致病菌经鉴定属于14大类,其中铜绿假单胞菌,170株,占22．91％;大肠埃希氏菌,145株,占19．54％;鲍曼不动杆菌,100株,占13,48％;产酸克雷伯菌,84株,占11．32％;其它10种G—致病菌所占的比例均小于8％。鲍曼不动杆菌、嗜麦芽假单胞菌、产气肠杆菌三种菌对检测的17种抗生素中的极少数敏感。在对17种抗生素的耐药性实验中,药效普遍较差的抗生素为:替卡西林、头孢呋辛、头孢噻吩三者的平均药敏感率依次为:20．72％、17.21％和11．71％。结论:临床G—致病菌的耐药性问题已非常严峻,降低G—致病菌的耐药性和控制其传播以迫在眉睫。
Objective： In order to provide the data resource for clinidans adopting antibiotics properly, we have researched the variety of the common pathogenic bacteria G- and the drug resistance of the commonly used antibiotics at present in our hospital. Methods： 742 stains of the pathogenic bacteria G- have been segregated from 3286 samples, then swains identifications and andmicrobial susceptibility tests have been done on them with the automatic microbion analysator vrrEK 32. Results： 742 strains of pathogenic bacteria G-belong to 14 categories, among which there are 170 strains of pseudomonas aeruginosa with a proportion of 22.91%; 145 strains of Escherichia coli, of 19.54%; 100 Baumanii, of 13.48%; 84 KlebsieUa oxytoca, of 11.32%; the others with a proportion less than 8%. Baumanii, Pseudomonas maltophilia and Enterobacter aerogenes are sensitive to few of these 17 detected antibiotics. In the drug resistance experiment, the antibiotics with a generally bad drug action are ticarcillin, cefuroxime and cafalotin, with a respective sensitivity rate of 20.72% , 17.21% and 11.71% . Conclusion： The drug resistance problem of the clinical pathogenic bacteria G- is rather serious, and it is imminent to cut down its drug resistance and to control its spreading.
出处
《现代生物医学进展》
CAS
2007年第3期378-380,386,共4页
Progress in Modern Biomedicine
关键词
G—致病菌
抗生素
药物监测
耐药性
Pathogenic bacteria G-
Antibiotics
Drug monitoring
Drug resistance
