摘要
目的研究莫西沙星治疗老年下呼吸道感染的临床疗效与安全性。方法搜集老年下呼吸道感染病例98例,对其用药前后的临床症状、体征、实验室检查和病原学检查,及肝肾功能相关指标进行分析。结果98例患者经莫西沙星治疗后急性支气管炎有效率为90.0%、慢性支气管炎急性发作(ABCE)为80.0%、慢性阻塞性肺疾病急性加重期(AECOPD)轻度为80%、中度为64.3%、重度为61.5%,慢性支气管炎并肺炎为54.5%。98例患者治疗中出现头晕3例、出现幻觉1例,所有患者用药前后肝肾功能相关指标变化无统计学意义。结论莫西沙星治疗老年下呼吸道感染疗效确切,安全。
Objective To evaluate the efficacy and safety of moxifloxacin in the treatment of elderly patients with infection of lower respiratory. Methods 98 elderly patients with infection of community and early hospital lower respiratory, which used moxifloxacin from June 2007 to August 2009 in dept. of deriatrics. Then to find the difference of those patients＇ signs and symptoms,laboratory examination,pathogens examination.ALT,AST,ALP,GGT,BUN,Cre and UA between the pretherapy and post-therapy. Results The efficacy rates was 90.0% of acutebronchitis, 80% of ABCE ,80% of mild- AECOPD,64.3% moderate-AECOPD,61.5% of severely-AECOPD and 54.5% of pneumonia. Three patienThreat of redun dancy dizzy,one patient felt illusioned.there was no significant difference （P〉0.05） of ALT AST GGT ALP BUN Cre and UA between the pretherapy and post-therapy. Conclusion Monxifloxacin in treatment of elderly patients with infection of community and early hospital lower respiratory was effective and safe.
出处
《中国老年保健医学》
2009年第4期85-87,共3页
Chinese Journal of Geriatric Care
关键词
莫西沙星
感染
下呼吸道
老年人
Moxifloxacin, Infection, Lower respiratory, Elderly
