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乳腺癌组织氧化应激反应指标的变化 被引量:12

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摘要 目的:探讨乳腺癌组织氧化应激反应指标的变化。方法:取8例女性原发性乳腺癌组织以及相应的癌旁组织为对照,应用化学比色法(参照试剂盒说明书)测定活性氧与丙二醛、谷胱甘肽含量以及谷胱甘肽过氧化物酶活性、超氧歧化酶活性。结果:乳腺癌组织与癌旁组织相比,活性氧与丙二醛的含量明显升高(P<0.05),谷胱甘肽含量、谷胱甘肽过氧化物酶活性、超氧歧化酶活性也明显升高(P<0.05)。结论:乳腺癌组织处于较强的氧化应激状态,其抗氧化能力也明显增强,进一步研究乳腺癌组织的氧化应激的机制和与乳腺癌组织的抗凋亡、浸润、转移的关系,将可能为深入了解乳腺癌发病机制和治疗提供一些新思路。
出处 《实用医学杂志》 CAS 北大核心 2009年第16期2626-2627,共2页 The Journal of Practical Medicine
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参考文献7

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