摘要
目的探讨实时MR成像引导下在猪脑动脉内进行导管插管的可行性。方法选用10只美国产的雌性小型猪作为实验对象。经皮穿刺股动脉,在实时MR成像引导下,将3F主动追踪微导管分别插至双侧咽升动脉内。解剖其主动脉弓、头臂动脉、颈动脉和咽升动脉,用肉眼观察有无穿孔、夹层等损害。结果MR血管成像证实,猪主要由双侧咽升动脉在颅底形成微血管网供应脑的血供。在实时MR(rtMR)成像引导下,对10只猪双侧咽升动脉进行插管操作,均操作成功,单次操作费时为4～12min。所有实验动物的主动脉弓、头臂动脉、颈动脉和咽升动脉的内壁均光滑完整,未发现血管壁损伤。结论实时MR成像引导下,可以将导管迅速、准确地插至猪脑动脉。
Objective To investigate the feasibility of catheterization of cerebral arteries under the real-time MR imaging guidance in experimental pigs. Methods Ten small-sized female pigs were selected for this study. Via the femoral access, percutaneous catheterization with a 3 F active MR-tracking microcatheter was performed under real-time MRI guidance and the mierocatheter was separately placed into bilateral ascending pharyngeal arteries. After the procedure, all the pigs were sacrificed and sent for pathologic examination. Gross pathologic examination of aortic arches, brachio-cephalic arteries, carotid arteries and ascending pharyngeal arteries was performed to search for the perforation and dissection. Results MR angiography revealed that in pigs the bilateral ascending pharyngeal arteries formed an arteriolar network at the cranial base, supplying blood flow to the brain. Catheterization of ascending pharyngeal arteries from the femoral artery access was successfully performed in all 10 pigs with the help of real-time MR imagingguidance. A single procedure took about 4 - 12 minutes. Macroscopically, no evidence of vascular injury of aortic arches, brachio-cephalic arteries, carotid arteries and ascending pharyngeal arteries was found. Conclusion Under real-time MRI guidance the catheterization of cerebral arteries can be correctly and quickly accomplished in experimental pigs.
出处
《介入放射学杂志》
CSCD
北大核心
2009年第7期521-525,共5页
Journal of Interventional Radiology
关键词
实时MR成像引导
脑动脉
导管插管
猪
real-time MR imaging guidance
cerebral artery
catheterization
pig
