摘要
胃癌组织中ＥＢ病毒的检出率因地区而异。为调查黑龙江地区胃癌ＥＢ病毒核酸的存在情况，我们用聚合酶链式反应（ＰＣＲ）法特异性扩增本地区经临床病理确诊的胃癌组织中ＥＢ病毒ＥＢＮＡ１基因区域，结果２９例标本中有６例检出ＥＢ病毒ＤＮＡ，且胃癌病理类型均是胃腺癌，提示本地区胃癌特别是胃腺癌的发生与ＥＢ病毒感染密切相关。
The appearence of Epstein-Barr virus (EBV)DNA in gastric carcinoma tissues were quite different according to geographic area.In order to investigate the existance of neucleic acid of EBV in gastric carcinoma specimens collected from Heilongjiang Province,the EBNA1 fragment of EBV was amplified by PCR from 29 gastric tissue specimens which had been confirmed as gastric carcinoma by clinical pathology in this experiment.Among them six were positive of EBV DNA,they were all gastric adenocarcinoma.It shows that the development of gastric carcinoma,especially,gastric adenocarcinoma,may be closed to the infection of Epstein-Barr virus.
出处
《哈尔滨医科大学学报》
CAS
1998年第4期238-240,共3页
Journal of Harbin Medical University
