摘要
目的探讨原发性脑淋巴瘤(PLB)的CT、MRI表现特征及病理基础。方法收集经手术、病理和免疫组化证实,资料齐全的PLB 17例,分析其CT、MRI及病理表现。结果17例患者中单发11例,多发6例,共25个病灶,分布于脑深部中线附近病灶19个(76.00%),分布于灰白质交界区及脑表面病灶6个(24.00%)。肿瘤形态多为类圆形肿块或结节,瘤周水肿多为轻至中度水肿。CT平扫多呈等密度或略高密度影。T1WI呈等、低信号,T2WI呈等、高信号,增强后呈明显均匀增强。B细胞来源的14例,多为LCA、CD20、CD79阳性;T细胞来源的3例,多为LCA、CD45RO、CD3阳性。结论PLB的病理学基础决定其CT及MRI表现特征,结合临床及影像学表现特征可以对该病作出正确诊断。
Objective To summarize the CT and MRI features of primary lymphoma of brain （PLB） as well as its pathogenesis. Methods 17 cases of PLB proven by operative findings, pathological and immuohistochemistry examination were collected. Their CT, MRI findings and the pathological conditions were retrospectively analyzed. Results Of 17 cases, the loci were single in 11 cases and multiple in 6 cases. There were 25 foci in total. 19 foci （76.00 % ） located in proximal deep brain of middle line, 6 foci （24.00 % ） in albocinereous junction and the surface of brain. Tumors presented node or mass, most foci showed mild or moderate edema. On CT scanning, the foci mostly appeared as isodensity or slightly high density. On MRI, the foci presented iso- or hypo - intense on TlWI while on T2WI it presented iso-or mildly hyper-intense relative to grey matter, the loci were homogeneously and markedly enhanced after contrast injection. 14 cases of PLB derives from B type cell, the LCA, CD20, CD79 were positive. 3 cases of PLB derives from T type cell, the LCA, CD45RO, CD3 were positive. Conclusions PLB have some CT and MRI features, which are determined by their corresponding pathologic characteristics. Correct diagnosis can be made in most cases when imaging findings are combined with clinical conditions.
出处
《右江民族医学院学报》
2009年第3期348-351,共4页
Journal of Youjiang Medical University for Nationalities
关键词
淋巴瘤
计算机体层摄影
磁共振成像
病理学
临床
lymphoma
computed tomography
magnetic resonance imaging
pathology, clinical
