摘要
体表慢性难愈合创面(俗称溃疡)是由一系列创伤和疾病所致。这类创面具有病程长、对外观影响大以及并发症多等特点,成为外科学中的一大难点问题。研究表明烧伤湿性医疗技术(MEBT/MEBO)对烧(创)伤创面具有改善微循环、祛腐生肌、促进创面再生与修复作用。本文通过综述分析MEBT/MEBO与慢性难愈合创面bFGF、VEGF的关系,明确MEBT/MEBO对慢性难愈合创面促进血管、细胞生长,加速创面愈合的分子生物学机制,阐述其基础研究现状和展望。
Cutaneous Chronic Wounds （commonly know as ulcers） is caused by a series of trauma and diseases. The wounds have a long course, bad appearance as well as more complications. It is therefore a major difficult problem of surgery. Research shows that MEBT/MEBO has the effect of improving microcirculation, clearing away the necrotic tissue, promoting wounds regeneration and repair. Base on the analysis of the effect of MEBT/MEBO on bFGF and VEGF in the chronic wounds, the mechanism of molecular biology of effect of MEBT/MEBO on promoting angiogenesis and cell growth, accelerating wound healing were discussed, and the present status and prospect of basic research of cutaneous chronic wounds treatment with MEBT/MEBO were described.
出处
《中国烧伤创疡杂志》
2009年第2期95-99,共5页
The Chinese Journal of Burns Wounds & Surface Ulcers
