摘要
采用免疫组化SP法，探讨了Nm23基因和C－erbB－2因表达与乳腺癌诸临床病理参数和预后的关系。其中Nm23阳性表达率：64．l％，C－erbB－2性率：50．64％。二基因表达与患者年龄无相关性，Nm23表达与组织类型及临床分期无明显关系，而与淋巴结转移及术后生存期有明显关系；C－erbB－2表达与癌组织学类型、淋巴结、临床分期和术后生存期都有关系。
The present paper has investigated the prognostic significance of Nm23 and C-erb B-2expression in 156 patients with breast cancer utilizing immunohistochemical staining S-Pmethod. The results show that Nm23 positive expression rate is 64. I percent (100/156)andC-erb B-2 positive expression rate is 50. 64 percent (79/156). Both of Nm23 and C-erb B-2expression have no correlation with age of the patients. Nm23 expression has no significantrelation with the histological type and clinical stage,but significantly relates with lymph nodemetastasis and postoperation survival time, C-erb B-2 expression significantly relates withhistological type,lymph node metastasis,clinical stage and postoperation survival time.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1998年第3期164-166,共3页
Cancer Research on Prevention and Treatment
