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儿童泌尿系统感染病原菌分布及耐药性分析 被引量:4

Analysis of fhe pathogens and antibotic resistance of urine cuine culture in children
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摘要 目的分析儿童尿培养病原菌的分布及耐药性,以期对临床泌尿系统感染的用药给予帮助。方法对2007年2月至2008年2月的所有尿培养的病原菌,用阳光半自动微生物鉴定和药敏系统进行鉴定和药敏试验。结果2007~2008年尿培养标本827例,共分离到病原菌146株,阳性率为17.7%。其中革兰阳性菌28株,占19.2%,居前3位的是凝固酶阴性葡萄球菌、粪肠球菌和尿肠球菌;革兰阴性菌110株,占75.3%,居前3位的是大肠埃希菌、肺炎克雷伯菌和奇异变形杆菌;真菌4株,占2.8%。共分离出大肠埃希菌68株,居首位,产超广谱β-内酰胺酶菌株55株(大肠埃希菌43株,肺炎克雷伯菌12株),占37.7%。结论儿童尿培养的病原菌仍以大肠埃希菌为主,多重耐药常见,了解病原菌分布特点及其耐药情况对临床合理选用抗生素具有重要意义。 Objective To analysis the pathogens and antibiltic resistance of urine culture in children in order to give some help in using the medicine in clinic. Methods All pathogens identified and done susceptibility by Yang- Guang Semi-automatic: Microbial system. Results In 2007-2008,827 urine sample sparated 146 pathogens,the positive rate is 17.3 %. Gram positive cocci accounted for 19.6 %, the majorty is Enterococcus faecalis, Enterococcus fasium and staphylococcus epidermidis,Graam negative bacilli accounter for 76.9 %, the Escherichia coli,klebsiella pneumoniae proteus mirabilis, fungi accountes for 2.1%, E. coli heading the list were separated by 68 strains. There is 37. 7 % producing extended-spectrum beta lactamases. Conclusion E. coli is the main pathogens of urine culture in children,and usually it is mull-resistant bacteria. It is important for the reasonable use of antibiotics to know the distribution and antibiotic resistance pf pathogens.
作者 何金凤
出处 《检验医学与临床》 CAS 2009年第11期848-849,851,共3页 Laboratory Medicine and Clinic
关键词 泌尿道感染 病原体 耐药性 尿培养 urinary tract infections pathogens antibiotic resistance urine culture children
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