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置入含消炎痛铜珠宫内节育器的子宫内膜形态计量学观察 被引量:8

Morphometric Study of the Endometrium from Patients Treated with Indomethacin-Releasing Copper Intrauterine Device
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摘要 本文研究置消炎痛铜珠宫内节育器3~6月后对防治带器出血的子宫内膜形态学观察.结果显示子宫内膜的增殖活性、炎性细胞反应、因子Ⅷ活性无明显差异(P>0.05).含消炎痛铜珠节育器可减少植入后因多形核白细胞、噬细胞增多,而纤溶活性增强的出血,并可调控血管功能而有助于置器后减少出血作用. In the present study,we investigated the endometrial change after insertion of indomethac in-releasing copper intrauterine device (IR -Cu -IUD) 3~6 months. Endometrial morphology, cell proliferation,inflammatory reaction and activity of complement Factor VI were examined. No sig-nificant difference was found (P>0. 05) in all the parameters examined in the same patients prior and after IR - Cu - IUD insertion. But comparing the data previously obtained from the patients with Cu -IUD insertion.it is clear that the amount of uterine bleeding after insertion of IR -Cu -IUD is much less. We suggest that the reduction of bleeding primarily contributes to the anti -in-flammatory action and reduction of fibrinolysis of indomethacin, which controls the function of vessels and helps to stop bleeding after insertion.
出处 《生殖与避孕》 CAS CSCD 北大核心 1998年第1期49-52,共4页 Reproduction and Contraception
关键词 含消炎痛铜珠宫内节育器 子宫内膜 形态计量学 因子Ⅷ IR-Cu-IUD Endometrium Mospbometric study FactorⅧ
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  • 1S. El-sahwi,M. Toppozada,M. Kamel,S. Gaweesh,W. Riad,I. Ibrahim,H. El-sabbagh. Prostaglandins and cellular reaction in uterine flushings. I. Effect of IUD insertion[J] 1987,Advances in Contraception(4):291~302 被引量:1
  • 2M. Toppozada,S. El-Sahwi,M. Kamel,W. Riad,S. Gaweesh,I. Ibrahim,H. El-Sabbagh. Prostaglandins and cellular reaction in uterine flushings. II. Effect of PG synthesis inhibition in IUD users[J] 1987,Advances in Contraception(4):303~313 被引量:1
  • 3S. El-sahwi,M. Toppozada,M. Kamel,S. Gaweesh,W. Riad,I. Ibrahim,H. El-sabbagh. Prostaglandins and cellular reaction in uterine flushings. I. Effect of IUD insertion[J] 1987,Advances in Contraception(4):291~302 被引量:1

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