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含消炎痛VCu200对月经失血量和血红蛋白影响的比较研究 被引量:15

A COMPARATIVE STUDY OF MENSTRUAL BLOOD LOSS AND HAEMOGLOBIN CHANGES IN WOMEN WEARING VCu 200 IUD CONTAINING OR NOT CONTAINING INDOMETHACIN
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摘要 本文用随机方法对185名健康妇女放置含消炎痛VCu 200(含药组)和不含消炎痛的VCu 200(不含药组)作为受试者,在放器前、后进行月经血量(MBL)、血红蛋白浓度(Hb)的测定。结果表明,置器后半年内,不含药组平均月经血量比含药组明显增多(P<0.01);血红蛋白值比含药组明显下降(P<0.01);半年后两组MBL、Hb值均无明显差别(P>0.05)。含药组放器前及后1,2,3,6,9,12周期的自身MBL、Hb值与不含药组自身对照相比,后者MBL明显增加,第一周期最为明显,增加达73%,直至第9周期基本恢复到放器前水平(P>0.05)。不含药组Hb值放器后明显下降,尤以第1、2周期最为明显,均下降9.0%含药组放器后MBL值略增加,Hb值略下降,但各周期与放环前相比差别无显著性(P>0.05)。不含药组放器后月经过多(MBL>80ml)、Hb<12g的发生率较高,以放器后半年内最为显著。含药组月经过多、Hb<12g的发生率均和放器前相仿,差别无显著性。 Menstrual Blood Loss (MBL) and Heamoglobin (Hb) were measured at pre- and 1 st, 2 nd, 3 rd, 6 th, 9 th, and 12 th post-insertion cycle in 185 women wearing the medicated IUDs (93 cases) and non-medicated IUDs (92 cases). The results demonstrated that the mean MBL of nonmedicated IUDs group was higher than that of the medicated IUDs group within the first 6 months of insertion (p<0.01). In the non-medicated IUDs group MBL of the first cycle after insertion had increased by 73% over the pre-inserion cycle and in the medicated IUDs group had increased by 10%. At the same time, MBL of the nonmedicated IUDs group in 1 st, 2 nd, 3 rd, 6 th, and 9 th post-insertion cycle significantly increased as compared with ehe pre-insertion cycle. The Hb of tht non-medicated IUDs group was sig- nificantly lower than that of the medicated IUDs group (p<0.01). The Hb of non-medicated IUDs group in the 1 st and 2 nd post-insertion cycle had decreased by 9.0% as Compared with the preinsertion cycle. In the medicated IUDs group there was no statistically difference of Hb before and after insertion (P>0.05). The incidence of menorrbea (MBL>80ml) or anemia (Hb<12g) was high in the non-medicated IUDs group and low in medicated IUDs group.
出处 《生殖与避孕》 CAS CSCD 北大核心 1990年第4期20-25,共6页 Reproduction and Contraception
关键词 月经血量 血红蛋白 VCU200 Menstrual blood loss Haemoglobin IUD containing Indomethacin
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参考文献1

  • 1S. El-sahwi,M. Toppozada,M. Kamel,S. Gaweesh,W. Riad,I. Ibrahim,H. El-sabbagh. Prostaglandins and cellular reaction in uterine flushings. I. Effect of IUD insertion[J] 1987,Advances in Contraception(4):291~302 被引量:1

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