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Cytotoxic triterpenoid saponins from Ardisia pusilla 被引量:4

Cytotoxic triterpenoid saponins from Ardisia pusilla
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摘要 A new triterpenoid saponin, 3-O-{ β-D-xylopyranosyl-(1 → 2)-β-D-glucopyranosyl-(1 → 4)-[β-D-glucopyranosyl-(1 → 2)]-α- L-arabinopyranosyl}-3β,16α,28α-trihydroxy-13β,28-epoxy-oleanan-30-al (ardipusilloside Ⅲ, 1), together with two known saponins, ardisiacrispins A (2) and B (3), were isolated from the whole plants of Ardisia pusilla A. DC. Their structures were elucidated by extensive spectral analysis and chemical evidences. Saponins 1 and 3 exhibited significant cytotoxicity against human glioblastoma U251MG cells. A new triterpenoid saponin, 3-O-{ β-D-xylopyranosyl-(1 → 2)-β-D-glucopyranosyl-(1 → 4)-[β-D-glucopyranosyl-(1 → 2)]-α- L-arabinopyranosyl}-3β,16α,28α-trihydroxy-13β,28-epoxy-oleanan-30-al (ardipusilloside Ⅲ, 1), together with two known saponins, ardisiacrispins A (2) and B (3), were isolated from the whole plants of Ardisia pusilla A. DC. Their structures were elucidated by extensive spectral analysis and chemical evidences. Saponins 1 and 3 exhibited significant cytotoxicity against human glioblastoma U251MG cells.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2009年第2期193-196,共4页 中国化学快报(英文版)
关键词 Ardisia pusilla Triterpenoid saponin Ardipusilloside Cytotoxic activities Ardisia pusilla Triterpenoid saponin Ardipusilloside Ⅲ Cytotoxic activities
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