摘要
大强度运动易导致骨骼肌损伤,并且骨骼肌损伤发生的机制比较复杂,涉及许多生理因素。人体在热应激状态下,会发生一定的应激性生理反应,并产生热休克蛋白,热休克蛋白是生物细胞在受到各种理化因素刺激下产生的一类高度保守的蛋白质,作为一种保护性蛋白,在维持细胞的自稳、保护细胞免受各种应激伤害中发挥了重要作用,并在骨骼肌中出现明显的强度依赖性。热应激适应对维持骨骼肌细胞正常功能起重要作用。
High intensity exercise may induce skeletal injury easily. There is very complicated mechanism in skeletal injury, which referring to many physiological factors. The stress physiological reaction would produce during the state of heat stress, including heat shock protein. Heat shock proteins, are a class of highly conserved proteins whose expression is increased when cells are exposed to elevated temperatures or other stress, which played the vital effect on the maintain of cell, or avoided the stress injury. It showed obvious dose-dependent in skeletal muscles. Heat stress response exhibits important role in maintaining the function of skeletal muscle cells.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2009年第11期2139-2142,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
